Medical uses Gabapentin

1 medical uses

1.1 seizures
1.2 pain
1.3 migraine
1.4 anxiety disorders
1.5 other uses

medical uses

gabapentin used treat seizures , neuropathic pain. commonly prescribed many off-label uses, such treatment of anxiety disorders, insomnia, , bipolar disorder. there are, however, concerns regarding quality of trials conducted , evidence such uses, in case of use mood stabilizer in bipolar disorder.

seizures

gabapentin approved treatment of focal seizures , mixed seizures. there insufficient evidence use in generalized epilepsy.

pain

a 2010 european federation of neurological societies task force clinical guideline based on available evidence recommended gabapentin first-line treatment diabetic neuropathy , postherpetic neuralgia highest level of evidence; recommended gabapentin first-line treatment central pain lower evidence. found evidence combination of gabapentin , morphine or oxycodone or nortriptyline worked better either drug alone; combination of gabapentin , venlafaxine may better gabapentin alone.

a 2017 cochrane review found evidence of moderate quality showing reduction in pain 50% in 15% of people postherpetic neuralgia , diabetic neuropathy. evidence finds little benefit , significant risk in chronic low pain. not known if gabapentin can used treat other pain conditions, , no difference among various formulations or doses of gabapentin found.

a 2010 review found may helpful in neuropathic pain due cancer. not effective in hiv-associated sensory neuropathy. , not appear provide benefit complex regional pain syndrome.

a 2009 review found gabapentin may reduce opioid use following surgery, not post-surgery chronic pain. 2016 review found not pain following knee replacement.

it appears effective pregabalin , costs less.

all doses appear result in similar pain relief.

migraine

the american headache society (ahs) , american academy of neurology (aan) guidelines classify gabapentin drug insufficient data support or refute use migraine prophylaxis. furthermore, 2013 cochrane review concluded gabapentin not useful prevention of episodic migraine in adults.

anxiety disorders

gabapentin has been used off label treatment of anxiety disorders. however, there dispute on whether evidence sufficient support being routinely prescribed purpose.

other uses

gabapentin may useful in treatment of comorbid anxiety in bipolar patients, (however not bipolar state itself). gabapentin may effective in acquired pendular nystagmus , infantile nystagmus, (but not periodic alternating nystagmus). effective in hot flashes. may effective in reducing pain , spasticity in multiple sclerosis. gabapentin may reduce symptoms of alcohol withdrawal (but not prevent associated seizures). there evidence role in treatment of alcohol use disorder; 2015 va/dod guideline on substance use disorders lists gabapentin weak , recommended second-line agent. use smoking cessation has had mixed results. gabapentin effective in alleviating itching in kidney failure (uremic pruritus) , itching of other causes. established treatment of restless legs syndrome. gabapentin may sleeping problems in people restless legs syndrome , partial seizures. gabapentin may option in essential or orthostatic tremor.

gabapentin not effective alone mood-stabilizing treatment bipolar disorder. there insufficient evidence support use in obsessive-compulsive disorder , treatment-resistant depression. gabapentin not appear effective treatment of tinnitus.