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Related conditions FMR1

1 related conditions 1.1 fragile x syndrome 1.2 fragile x-associated tremor/ataxia syndrome 1.3 premature ovarian aging 1.4 polycystic ovarian syndrome related conditions fragile x syndrome almost cases of fragile x syndrome caused expansion of cgg trinucleotide repeat in fmr1 gene. in these cases, cgg abnormally repeated 200 more 1,000 times. result, part of fmr1 gene methylated, silences gene (it turned off , not make protein). without adequate fmrp, severe learning deficits or mental retardation can develop, along physical abnormalities seen in fragile x syndrome. fewer 1% of cases of fragile x syndrome caused mutations delete part or of fmr1 gene, or change base pair, leading change in 1 of amino acids in gene. these mutations disrupt 3-dimensional shape of fmrp or prevent protein being synthesized, leading signs , symptoms of fragile x syndrome. a cgg sequence in fmr1 gene repeated between 55 , 200 times described premutation. although individuals premutation intellectually normal...

Genus cirrus List of cloud types

cirrus uncinus clouds (v-2) cirrus spissatus (v-3) clouds cirrus fibratus radiatus (v-8) abbreviation: ci cirriform clouds tend wispy , transparent or translucent. isolated cirrus not bring rain; however, large amounts of cirrus can indicate approaching storm system followed fair weather. there several variations of clouds of cirrus genus based on species , varieties: species cirrus fibratus (v-1) high clouds having traditional mare s tail appearance. these clouds long, fibrous, , curved, no tufts or curls @ ends. cirrus uncinus (v-2) filaments up-turned hooks or curls. cirrus spissatus (v-3) dense , opaque or opaque patches. cirrus castellanus (v-4) a series of dense lumps, or towers , connected thinner base. cirrus floccus (v-5) elements take on rounded appearance on top, lower part appearing ragged. opacity-based varieties none; translucent except species spissatus inherently opaque. fibratus pattern-based varieties cirrus fibratus intortus (v-6) irregularly curved or tangled fil...

Final table 2005–06 Ukrainian First League

fc nyva vinnytsia (5th persha liha 2004-05) merged operations fc bershad (5th druha liha hrupa 2004-05) , moved bershad , renamed club prior start of season. 3 points deducted fc bershad failure comply federation directives (12/16/2005) , 6 points (9 total) deducted continual nonconformance of league directives (2/24/2006) informed uff team dissolved , not play more matches. (may 19, 2006) legend:

Composition Synaptic vesicle

primary hippocampal neurons observed @ 10 days in vitro confocal microscopy. in both images neurons stained somatodendritic marker, microtubule associated protein (red). in right image, synaptic vesicles stained in green (yellow green , red overlap). scale bar = 25 μm. synaptic vesicles relatively simple because limited number of proteins fit sphere of 40 nm diameter. purified vesicles have protein:phospholipid ratio of 1:3 lipid composition of 40% phosphatidylcholine, 32% phosphatidylethanolamine, 12% phosphatidylserine, 5% phosphatidylinositol, , 10% cholesterol. synaptic vesicles contain 2 classes of obligatory components: transport proteins involved in neurotransmitter uptake, , trafficking proteins participate in synaptic vesicle exocytosis, endocytosis, , recycling. transport proteins composed of proton pumps generate electrochemical gradients, allow neurotransmitter uptake, , neurotransmitter transporters regulate actual uptake of neurotransmitters. necessary proton gradient...

Europe Real estate investment trust

1 europe 1.1 belgium 1.2 bulgaria 1.3 finland 1.4 france 1.5 germany 1.6 ireland 1.7 united kingdom europe over past few years new reit regimes have been introduced in europe meet growing demand investors tax efficient real estate investments vehicles, existing reit regime in europe have been improved. in europe, top-performing reit , largest publicly traded real estate company unibail-rodamco se. belgium belgian reits introduced bernheim comofi (now ag real estate) in 1995 constitution of befimmo. others reits in belgium include cofinimmo , ascensio. bulgaria reits introduced in bulgaria in 2004 special purpose investment companies act. pass-through entities corporate income tax purposes (i.e., not subject corporate income tax), subject numerous restrictions. finland finnish reits established in 2010, when tax exemption law (laki eräiden asuntojen vuokraustoimintaa harjoittavien osakeyhtiöiden verohuojennuksesta, 299/2009) passed finnish parliament. law on real estate funds (kiint...

1♣ opening Polish Club

1 1♣ opening 1.1 1♦ response 1.2 1♥/1♠ responses 1.3 1nt response 1.4 2♣/2♦ responses 1.5 2♥/2♠ responses 1.6 2nt response 1.7 3♣/3♦ response 1.8 3♥/3♠ responses 1♣ opening 1♦ response 1♣ - 1♦ ? 1♥/1♠ = better major (3 cards possible) 1nt = 18–19 hcp, balanced 2♣ = 15+ hcp, natural 2♦ = artificial gf, exclusive of 2-suiter hands 2♥, 2♠, 3♣, 3♦ = 5+ in bid suit, semi-forcing 2nt = 22–24 hcp, balanced 3♥/3♠/4♣ = gf, 2-suiter (5-5): 3♥ – hearts, responder’s 3♠ shows preference on hearts, 3nt asks minor, 4♣, 4♦ cue bids agreed hearts, 3♠ – spades , minor, 3nt asks minor, 4♣, 4♦ cue bids, 4♣ – minors. 1♥/1♠ responses 7+hcp, 4+ cards, can have longer minor if less gf 1♣ - 1♥/1♠ ? 2♣ = 15+, one-round force, responder’s 2♦ forces game. 2♦ = relay, 18+ hcp, promises @ least 3 cards in responder’s major. 2♥ = (after 1♠ response) 5+♥, (18+ hcp), gf 2nt = 18+ hcp, (semi-)balanced, denies 3-card support in responder’s suit. after 1♣-1♥/1♠-2♦, responder bids follows ( bubrotka ): 2♥ = 7–10 hcp, 4 ca...

Technique and innovations in color photography Ernst Haas

ernst haas, la suerte de capa, pamplona, spain, 1956 though haas continued use black-and-white film of career, color film , visual experimentalism became integral photography. employed techniques shallow depth of field, selective focus, , blurred motion create evocative, metaphorical works. became interested in, put it, transforming object what want be. beyond physical place, person, or object depicted, haas hoped reflect joy of looking , of human experience. haas supported adventurous personal work commercially viable photojournalism, advertising, , motion picture stills photography. while on such assignments, make own photographs, translating passion poetry, music, painting, , adventure color imagery. reputation on rise, haas traveled world, photographing u.s., europe, south africa, , southeast asia in expressionistic color. in late 1940s, haas switched medium format rolleiflex smaller 35mm leica rangefinder camera, used consistently rest of career. once began working in color, use...